منابع مشابه
Clinical benefit of metaphase I oocytes
BACKGROUND We studied the benefit of using in vitro matured metaphase I (MI) oocytes for ICSI in patients with a maximum of 6 mature metaphase II (MII) oocytes at retrieval. METHODS In 2004, 187 ICSI cycles were selected in which maximum 6 MII oocytes and at least one MI oocyte were retrieved. MI oocytes were put in culture to mature until the moment of ICSI, which was performed between 2 to ...
متن کاملNondisjunctional Segregations in Drosophila Female Meiosis I Are Preceded by Homolog Malorientation at Metaphase Arrest
The model of Drosophila female meiosis I was recently revised by the discovery that chromosome congression precedes metaphase I arrest. Use of the prior framework to interpret data from meiotic mutants led to the conclusion that chromosome segregation errors (nondisjunction, NDJ) occurred when nonexchange chromosomes moved out on the spindle in a maloriented configuration and became trapped the...
متن کاملActivation of Akt (protein kinase B) stimulates metaphase I to metaphase II transition in bovine oocytes.
In somatic cells, the serine/threonine kinase Akt (or protein kinase B) was shown to contribute to processes linked to cellular growth, cell survival and cell cycle regulation. In contrast to these findings, the function of Akt during the meiosis of mammalian oocytes remains to be investigated. We analysed the phosphorylation pattern and the activity of Akt during meiotic maturation (transition...
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Bacterial RecA and its yeast orthologue RAD51 are the founding members of the RecA/RAD51 protein family, which plays a crucial role in DNA repair by homologous recombination (for review see Kawabata et al., 2005). After DNA ends are resected at the site of a DNA break, these proteins form a nucleoprotein fi lament on the single-stranded DNA and catalyze a strand invasion and strand exchange rea...
متن کاملProduction of Live Offspring from Vitrified-Warmed Oocytes Collected at Metaphase I Stage
Vitrification of matured oocytes is widely adopted in human clinics and animal research laboratories. Cryopreservation of immature oocytes, particularly those at metaphase I (MI), remains a challenge. In the present work, mouse MI oocytes denuded of cumulus cells were vitrified and warmed (V/W) either prior to (V/W-BEFORE-IVM, n = 562) or after (V/W-AFTER-IVM, n = 664) in vitro maturation (IVM)...
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ژورنال
عنوان ژورنال: Caryologia
سال: 1995
ISSN: 0008-7114,2165-5391
DOI: 10.1080/00087114.1995.10797338